Fan ZJ, Liu JM, Li XX, et al. View abstract. J Clin Psychopharmacol 2008;28(3):264-370. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. J Cancer Res Ther. Myopathies associated with red yeast rice and liquorice: spontaneous reports from the Italian Surveillance System of Natural Health Products. van der Zwan A. Murakami, T. and Uchikawa, T. Effect of glycyrrhizine on hyperkalemia due to hyporeninemic hypoaldosteronism in diabetes mellitus. If you take birth control pills along with peony, use an additional form of birth control such as a condom. View abstract. View abstract. View abstract. Eur J Dermatol. View abstract. Pharm Biol 2021;59(1):1276-1285. Migraine. About Dr.Cope. View abstract. A dual investigation of the effect of dietary supplementation with licorice flavonoid oil on anthropometric and biochemical markers or health and adiposity. View abstract. Am J Chin Med 1992;20(3-4):313-317. 2013 Sep;117(3):614-21. The combination of licorice and white peony can help to decrease the excess testosterone that is being produced by the ovaries in PCOS. View abstract. Licorice consumption and serum testosterone in healthy man. Results of a double-blind placebo controlled comparative study]. View abstract. J Pharmacobiodyn 1984;7:304-11. Nephron 2002;90:240. Here are a few of them: . Inhibition of 11 beta hydroxysteroid dehydrogenase obtained from guinea pig kidney by furosemide, naringenin and some other compounds. 1986;6(12):714-6, 707. 2020 Dec;58(1):352-356. Am J Epidemiol 2001;153:1085-8. View abstract. View abstract. Chin, Y. W., Jung, H. A., Liu, Y., Su, B. N., Castoro, J. Protective effects of peony root extract and its components on neuron damage in the hippocampus induced by the cobalt focus epilepsy model. View abstract. Acute myopathy associated with chronic licorice ingestion: reversible loss of myoadenylate deaminase activity. Rosenblat, M. and Aviram, M. Paraoxonases role in the prevention of cardiovascular diseases. Gardner Z, McGuffin M. Boca Raton, FL: CRC Press, 2013. Gao, X., Wang, W., Wei, S., and Li, W. [Review of pharmacological effects of Glycyrrhiza radix and its bioactive compounds]. 2010;33(2):321-324. Am J Chin Med 2003;31:445-53. . Messier, C., Epifano, F., Genovese, S., and Grenier, D. Licorice and its potential beneficial effects in common oro-dental diseases. Int J Nurs Stud 2016;63:9-17. Ann Clin Biochem 2007;44(Pt 4):397-399. $9.44 $ 9. Food Chem Toxicol 1993;31:303-12. View abstract. Paeoniflorin's. Herb-Drug Interaction Potential of Licorice Extract and Paclitaxel: A Pharmacokinetic Study in Rats. Red Peony Root (Paeniae Rubra Radix) 8 g Myrrh (Myrrha) . Liang, R. N., Liu, J., and Lu, J. View abstract. Menati L, Khaleghinezhad K, Tadayon M, Siahpoosh A. J Clin Hypertens (Greenwich) 2008;10:153-7. Peony-glycyrrhiza decoction, an herbal preparation, inhibits clozapine metabolism via cytochrome P450s, but not flavin-containing monooxygenase in in vitro models. Dehours E, Vall B, Roug-Bugat ME, Florent B, Bounes V, Franchitto N. Suspected hypokalaemia following liquorice ingestion on board ship. Eur J Drug Metab Pharmacokinet. Hum Exp Toxicol 2012;31(12):1295-1298. View abstract. 2004;4(3):377-386. Ruiz-Granados, E. S., Shouls, G., Sainsbury, C., and Antonios, T. A salty cause of severe hypertension. Peony might change how quickly the liver breaks down these medications. View abstract. 2010;16(4):216-218. Grapefruit juice and its flavonoids inhibit 11 beta-hydroxysteroid dehydrogenase. Zhou, Y., Huang, Z., and Huang, T. [Clinical study of shengxue mixture in treating aplastic anemia]. Zhong.Xi.Yi.Jie.He.Za Zhi. A systemic review and meta-analysis of the clinical efficacy and safety of total glucosides of peony combined with methotrexate in rheumatoid arthritis. Beretta-Piccoli, C., Salvade, G., Crivelli, P. L., and Weidmann, P. Body-sodium and blood volume in a patient with licorice-induced hypertension. Biol Pharm Bull. Strandberg TE, Andersson S, Jarvenpaa AL, et al. Efficiency and safety of desloratadine in combination with compound glycyrrhizin in the treatment of chronic urticaria: a meta-analysis and systematic review of randomised controlled trials. View abstract. A., Lee, S. H., and Lee, S. M. Protective mechanism of glycyrrhizin on acute liver injury induced by carbon tetrachloride in mice. 2014 Jan;35(1):87-99. An Bras Dermatol 2010;85(5):613-620. Fang, J. Y. Lorenzin, F., Degen, C., Milani, A., Siciliano, M., and Rossi, L. [Pseudo-hyperaldosteronism caused by licorice. Early evidence suggests that taking 45 grams of a specific product containing peony and licorice (Peony-Glycyrrhiza Decoction, PGD) daily for 4 weeks reduces levels of a hormone called prolactin in women with high levels of prolactin, without affecting other hormone levels or mental symptoms. Heidemann HT, Kreuzfelder E. Hypokalemic rhabdomyolysis with myoglobinuria due to licorice ingestion and diuretic treatment. 2016 Oct;39:314-319. doi: 10.1016/j.intimp.2016.08.006. View abstract. View abstract. Wen Y, Tang Y, Li M, Lai Y. Kraus SD, Kaminskis A. View abstract. Licorice, tobacco chewing, and hypertension. It contains kojic acid, witch hazel, and licorice extracts that reduce melanin production and exfoliate . View abstract. J Ethnopharmacol 2002;81:101-4.. View abstract. van Rossum, T. G., Vulto, A. G., Hop, W. C., and Schalm, S. W. Glycyrrhizin-induced reduction of ALT in European patients with chronic hepatitis C. Am J Gastroenterol 2001;96(8):2432-2437. Engqvist, A., von Feilitzen, F., Pyk, E., and Reichard, H. Double-blind trial of deglycyrrhizinated liquorice in gastric ulcer. Other conditions. Celery juice has become very popular now as it is believed to cure many health problems including obesity, thyroid, gout, blood pressure and fluid retention. Nussbaumer, U., Landolt, M., Rothlisberger, G., Akovbiantz, A., Keller, H., Weber, E., Blum, A. L., and Peter, P. [Postoperative stress hemorrhage: ineffective prevention with pepsin inhibitor and deglycyrrhizinized licorice extract. View abstract. Allergic contact dermatitis to Glycyrrhiza inflata root extract in an anti-acne cosmetic product. . Licorice might decrease how quickly the body breaks down methotrexate. View abstract. 1988;8(11):660-2, 645. Aliment Pharmacol Ther 2004;20:1279-87. View abstract. View abstract. Nahidi F, Zare E, Mojab F, Alavi-Majd H. Effects of licorice on relief and recurrence of menopausal hot flashes. 4-14-2001;145(15):744-747. View abstract. Arentz S, Smith CA, Abbott J, Fahey P, Cheema BS, Bensoussan A. Lee, C. H., Park, S. W., Kim, Y. S., Kang, S. S., Kim, J. Grebeniuk, V. N., Mannanov, A. M., Korsun, V. F., and Vinogradova, A. I. Lancet 2-10-1979;1(8111):319. View abstract. Feng ZT, Xu J, He GC, Cai SJ, Li J, Mei ZG. Case 30-2020: A 54-Year-Old Man with Sudden Cardiac Arrest. Immunopharmacology 1999;41(3):169-181. Concomitant Use of High-dose Methotrexate and Glycyrrhizin Affects Pharmacokinetics of Methotrexate, Resulting in Hepatic Toxicity. Mechanism of anti-inflammatory action of glycyrrhizin: effect on neutrophil functions including reactive oxygen species generation. Licorice root and white poney is a common herbal formula for PCOS originating in traditional Chinese medicine. The Potential Benefits and Side Effects of the White Peony Root. J Hum Hypertens 2001;15:549-52. Neurology 2010;75(21):1939-1941. Peony (Paeonia lactiflora) is an herb. Cardiovasc.Drugs Ther 1998;12(6):599-600. We currently have no information for PEONY overview. Iran J Pharm Res 2012;11(2):541-8. Amato P, Christophe S, Mellon PL. Peony and its major constituent, paeoniflorin, improve radial maze performance impaired by scopolamine in rats. View abstract. is tatcha violet c brightening serum safe for pregnancy is tatcha violet c brightening serum safe for pregnancy View abstract. QJM 2011;104(12):1093-1095. J Am Coll.Nutr 2007;26(3):209-218. Zhang W, Dai SM. Kormann R, Languille E, Amiot HM, Hertig A. 1979;14(5):605-607. [RETRACTED]. Proanthocyanidins, flavonoids, tannins, polysaccharides, and paeoniflorin are all considered to contribute to the medicinal activity of various forms of peony. View abstract. Traditional Chinese medicines Wu Wei Zi (Schisandra chinensis Baill) and Gan Cao (Glycyrrhiza uralensis Fisch) activate pregnane X receptor and increase warfarin clearance in rats. View abstract. J Altern Complement Med 2000;6:557-9. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Effects of Paeonia lactiflora root extracts on the secretions of monocyte chemotactic protein-1 and -3 in human nasal fibroblasts. 2005 - 2023 WebMD LLC. Inflammopharmacology 2022;30(2):477-486. View abstract. View abstract. View abstract. 2000;20(3):173-175. Licorice (Glycyrrhizae Radix) 15 g: NR: Zhao (2016) [36] . View abstract. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Deng, Y. Y., Chen, Y. P., Wang, L., Hu, Z., Jin, Y., Shen, L., Zhu, R., and Zhong, Y. View abstract. 1999;15:499-523. World J Gastroenterol 2005;11:2124-9. . View abstract. View abstract. 2019;33(1):117-29. Lancet 1992;340:13-17. October 15, 2021. Lancet 1990;335(8697):1060-3. Robles BJ, Sandoval AR, Dardon JD, Blas CA. Volatiles with antimicrobial activity from the roots of Greek Paeonia taxa. Phytother.Res. Planta Med 1983;48(5):38-42. Z Kardiol 1991;80(6):389-391. Licorice might increase how quickly midazolam is broken down by the body. View abstract. Sucking on a licorice lozenge or gargling with a licorice fluid shortly before placement of a breathing tube seems to help prevent cough and. Francini-Pesenti F, Puato M, Piccoli A, Brocadello F. Liquorice-induced hypokalaemia and water retention in the absence of hypertension. View abstract. The glycyrrhizin and glycyrrhetic acid constituents of licorice have significant anti-androgen effects, 32-34 which may be helpful in reducing androgenic symptoms in women with PCOS. View abstract. Izv Akad Nauk Ser Biol 1997;2:235-7. . Muscle cramps.Early research suggests that taking a specific combination of peony and licorice (Shakuyaku-kanzoh-to) might ease muscle cramps in people with liver cirrhosis and in people undergoing hemodialysis. Ultrastruct Pathol 1992;16(5):529-535. Cancer 1997;79(8):1494-1500. WebMD does not provide medical advice, diagnosis or treatment. Peony-glycyrrhiza decoction for antipsychotic-related hyperprolactinemia in women with schizophrenia: a randomized controlled trial. [Comparison of pre- and post-treatmental hepatohistology with heavy dosage of Paeonia rubra on chronic active hepatitis caused liver fibrosis]. Kim YR, Nam SH. Iran J Pharm Res. Growth-inhibiting, bactericidal, and urease inhibitory effects of Paeonia lactiflora root constituents and related compounds on antibiotic-susceptible and -resistant strains of Helicobacter pylori. Chem Pharm Bull (Tokyo) 1994;42(5):1056-1062. White Peony Tea Side Effects. View abstract. Lancet 2000;355(9198):134-138. View abstract. Ann Pharmacother 2003;37(6):836-838. This week, The New England Journal of Medicine reported that a man with a poor diet died of cardiac arrest after eating a bag-and-a-half of black licorice daily for weeks. Anon. Ital.J Neurol.Sci 1997;18(4):217-220. 2019;18(Suppl1):291-301. Yamashiki, M., Nishimura, A., Suzuki, H., Sakaguchi, S., and Kosaka, Y. Contact Dermatitis 2008;59(1):52. Ir J Med Sci 2016;185(4):945-7. Wu, T. H., Chiu, T. Y., Tsai, J. S., Chen, C. Y., Chen, L. C., and Yang, L. L. Effectiveness of Taiwanese traditional herbal diet for pain management in terminal cancer patients. 2008;9(3):88-98. Life Sci 2-23-2001;68(14):1687-1694. Antiviral Res 2003;59(1):41-47. Liquorice supplements View abstract. 2017 Sep;31(9):1330-1340. Astragalus may be safe when used orally and appropriately. Loop diuretics can also decrease potassium levels. The chemicals in licorice are thought to . The treatment of human cancer with agents prepared from bovine cartilage. Drug Metab Dispos 2015;43(7):1147-53. Tu, J. H., He, Y. J., Chen, Y., Fan, L., Zhang, W., Tan, Z. R., Huang, Y. F., Guo, D., Hu, D. L., Wang, D., and Hong-Hao Zhou. J Infect.Chemother. View abstract. Jin, C. Y., Wang, D. L., and Fang, Z. D. [Effect of integrative Chinese and Western medicine in treating chronic urticaria and its impact on interleukin-10 and interleukin-8 in peripheral blood]. View abstract. Removes excess melanin: Licorice extract brightens the skin in another way, too. View abstract. According to research, the combination of . [Treatment of refractory polycystic ovary syndrome by bushen huoxue method combined with ultrasound-guided follicle aspiration]. Roussak NJ. The effect of dong quai on menopausal symptoms is unknown. The anti-estrogenic action of beta-glycyrrhetinic acid. Taking licorice might reduce the effects of blood pressure medications. Huang, W. W., Wang, M. Y., Shi, H. M., Peng, Y., Peng, C. S., Zhang, M., Li, Y., Lu, J., and Li, X. Phytomedicine 2003;10:271-85. The immediate effect of Shakuyaku-kanzo-to, traditional Japanese herbal medicine, for muscular cramps during maintenance hemodialysis. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. View abstract. It is used for stomach pain, abdominal pain and acute pain of gastrocnemius muscle contracture, etc. Johns, C. Glycyrrhizic acid toxicity caused by consumption of licorice candy cigars. Martin, M. D., Sherman, J., van der Ven, V., and Burgess, J. Fujisawa, Y., Sakamoto, M., Matsushita, M., Fujita, T., and Nishioka, K. Glycyrrhizin inhibits the lytic pathway of complement--possible mechanism of its anti-inflammatory effect on liver cells in viral hepatitis. View abstract. [Effect of fu-zheng qu-xie on gastric disease infected with Campylobacter pyloridis]. View abstract. Kent UM, Aviram M, Rosenblat M, Hollenberg PF. Sontia B, Mooney J, Gaudet L, Touyz RM. Liquorice and hypertension. Wu G, Wu N, Li T, et al. Braz J Infect Dis 2016;20(6):534-8. Taking licorice along with estrogen might decrease the effects of estrogen. A preliminary open trial on interferon stimulator (SNMC) derived from Glycyrrhiza glabra in the treatment of subacute hepatic failure. Neth J Med 2005;63:146-8. Sakamoto S, Kudo H, Suzuki S, et al. View abstract. Clin Neurol Neurosurg 1993;95(1):35-37. Baba, M. and Shigeta, S. Antiviral activity of glycyrrhizin against varicella-zoster virus in vitro. A specific type of peony product, total glucosides of peony (TGP), has most often been used by adults in doses of 600 mg by mouth three times daily for up to 24 weeks. Acta Endocrinol (Buchar) 2020;16(4):508-510. View abstract. View abstract. 2018 Jan;37(1):35-42. doi: 10.1007/s10067-017-3770-y. View abstract. Isr J Dent Sci 1989;2(3):153-157. Armanini D, De Palo CB, Mattarello MJ, et al. Oh, G. S., Pae, H. O., Choi, B. M., Lee, H. S., Kim, I. K., Yun, Y. G., Kim, J. D., and Chung, H. T. Penta-O-galloyl-beta-D-glucose inhibits phorbol myristate acetate-induced interleukin-8 [correction of intereukin-8] gene expression in human monocytic U937 cells through its inactivation of nuclear factor-kappaB. van Rossum, T. G., Vulto, A. G., Hop, W. C., and Schalm, S. W. Pharmacokinetics of intravenous glycyrrhizin after single and multiple doses in patients with chronic hepatitis C infection. Licorice extract inhibits the production of tyrosinase, in turn inhibiting the production of dark spots. CJEM 2010;12(3):224-225. Clinical application of compound Glycyrrhizin tablets in the treatment of patients with Simplex Henoch-Schonlein Purpura and its effect on immune function. View abstract. Zangooei Pourfard M, Mirmoosavi SJ, Beiraghi Toosi M, et al. A. An Med Interna 1995;12(1):33-35. View abstract. View abstract. A., Torres Murillo J., and Calderon de la Barca Gazquez J. M. [Acute rhabdomyolysis and tetraparesis secondary to hypokalemia due to ingested licorice]. Du, J. H. and Dong, B. D. [Comparative study on clinical efficacy of using methotrexate singly or combined with total glucosides of Paeony in treating rheumatoid arthritis]. Zhu Q, Qi X, Wu Y, Wang K. Clinical study of total glucosides of paeony for the treatment of diabetic kidney disease in patients with diabetes mellitus. View abstract. Phytother.Res 2004;18(3):241-243. van Rossum, T. G., Vulto, A. G., Hop, W. C., Brouwer, J. T., Niesters, H. G., and Schalm, S. W. Intravenous glycyrrhizin for the treatment of chronic hepatitis C: a double-blind, randomized, placebo-controlled phase I/II trial. Treatment of duodenal ulcer with glycyrrhizinic-acid-reduced liquorice. A botanical dietary supplement from white peony and licorice attenuates nonalcoholic fatty liver disease by modulating microbiota and reducing inflammation . View abstract. View abstract. Akbari N, Asadimehr N, Kiani Z. Arch Pharm Res 2003;26(10):832-839. View abstract. View abstract. J Gastroenterol Hepatol 1999;14(11):1093-1099. Brayley J, Jones J. Life-threatening hypokalemia associated with excessive licorice ingestion (letter).