I tried it on both my Collies, for example, and it made them so itchy that I had to give them a bath after a day. I know Simparica is more convenient since it means giving one monthly preventive instead of two, but the trade-off with the combo meds is that theyre usually stronger. Thank you for such a great article! Are you also on Instagram, by chance? Simparica. According to the product description, side effects as a result of Trifexis are rare, but can be as severe as seizures or even a coma. Simparica Trio is the first and only product that combines sarolaner, moxidectin, and pyrantel in one simple-to-give chewable-for protection against heartworm disease, ticks & fleas, roundworms & hookworms.. One chewable tablet provides month-long protection for all dogs over 8 weeks old and weighing 2.8 pounds or more. For dogs who have a case of mange or ear mites, the treatment can involve topical applications of compounds containing (you guessed it) Ivermectin. Thank you! In summary, use with caution. Later, the vet had the experience of this happening to other cats and one of his own. (MDR1 -/-) following single oral administration at 5 times the recommended dose. Please log in again. Im happy to hear it and so glad it helped! One thing about Credelio is that it only breaks the flea life cycle at one point (kills adult fleas only after they bite the dog), so you may want to use a natural flea & tick repellent spray to increase its effectiveness. I know youre very particular about the genetic health of your Collies, and I admire your breeding program. Sarolaner is an . Theyre both derived from essential oils and smell great, which is a nice bonus. Thats a good point about the potentially smaller user sample size for Credelio, since its a newer medication that hasnt been out as long as the others. Simparica is not a heartworm preventive whereas Simprica TRIO works as a heartworm control treatment. From the standpoint of MDR1 dogs, it is safe. (One such knockoff, Pet Armor Plus, is even available at Walmart.). Is Simparica trio safe for dogs with the MDR1 gene? Id like to have a Smooth Collie in the future. I did write this article a couple of years ago; but I have updated it several times since most recently after information came out about some fatal reactions to Seresto collars. Advantage takes care of fleas at all life stages and is even supposed to kill them on contact, and it also covers lice. As noted in an article by Dog Aware:Advantage Multi, which combines imidacloprid for flea control with moxidectin for heartworm prevention, was found to cause no side effects when applied topically to affected dogs even at 5 times the recommended dose, but ingesting less than half the recommended topical dose caused extreme toxicity leading to coma in four of five dogs.. It can be used to destroy bedbugs, cockroaches, ants, and even fleas. Is this true? SIMPARICA TRIO tested positive for heartworm disease. Theyre so fun and crazy at that age. Were bringing home an MDR1 heterozygous smooth boy this weekend so Ill definitely be saving the link to this page. Simparica Trio is generally well tolerated at the recommended dose; adverse reactions (t ransient ataxia and/or muscle fasciculation in dogs with a deficient multidrug -resistance-protein 1 (MDR1 -/-)) are only seen at overdoses. Multi-Drug Resistance 1 (MDR1) is a gene that is meant for helping to protect the brain. But it doesnt hurt mammals. I just dont know what to do about heartworm treatment and wonder if Interceptor instead of Interceptor Plus would be a better option or more of the same. Simparica Trio 11.1-22 lbs. Bear in mind a dog can negatively react to anything though, so its always best practice to keep a close eye on them after administering any new product! (Your vet or a pet store associate may recommend otherwise, but bear in mind that they also want to make money.). It protects your dog against fleas and paralysis ticks, intestinal worms and deadly heartworm. I have a cat myself, so I appreciate the information. Freckles my Aussie/Pyr is such a great dog. Please tell me if I am wrong. According to Dog Aware, most flea and tick control medications have not been found to cause adverse effects when used as directed, but toxicity can occur iftopicalproducts areingested. This is why reading labels is so important. Thank you for the warning. Excellent research and well written article! Ive talked to Collie and Aussie owners who absolutely swear by their Seresto collars and others who are livid because they made their dogs neck bald! Im glad you found it helpful. Giardia can be passed to and cause diarrhea in humans. Fleas were treated with effifax, active ingredient fipronil. Material name: Simparica Trio Version #: 01 Issue date: 07-01-2019 SDS US. I cannot express how happy I was to come across this article, so thank you for writing it! Simparica TRIO. I was bummed to read its the safest since I dont want him to have it every again (a little off balance shortly after and salivating) but later he had an episode with fixed eyes, stuck in a strange position, stiff muscles, blind, he had a heart rate half of what it should have been and a head tremor. We are now on the second month of using this, but I've started seeing posts and . They said Frontline Plus doesnt really work anymore like it used too. is it safe or not to use it? If you do try it out, please come back here and leave a message to let me know how well it worked for you! Thanks for your informative article. Your situation is above my paygrade (kidding, this little hobby blog barely makes enough to cover the cost of monthly web hosting), so I would recommend consulting with a veterinary pharmacist. It also helps to know your dogs MDR1 statuses, which can be checked through places like Paw Print Genetics. For the treatment and control of tick infestations with Amblyomma americanum (lone star tick) and Ixodes scapularis . She is just 1 year old. My dog has been tested and is mutant/normal (MDR1). Revolution and Stronghold even tested safe over the recommended monthly dosage for dogs with the MDR1 gene, and they hold the distinction of being the only heartworm meds that did not produce any negative drug reactions. The flea pills and chews all contain a pesticide called isoxazoline, the FDA said . (357 reviews) Simparica. Giardia can be passed to and cause diarrhea in humans. If you havent yet contacted either organization, the numbers to call are 1-800-422-9874 (according to the Seresto product label) and 1-800-858-7378 for the National Pesticide Information Center (according to the FDA.gov website). Many Rough Collie owners swear by them, and one owner mentioned that she lives in the woods and the Seresto collars kept the ticks off her Roughs. I have a unique situation. My question is about Capstar. It made my Collies itch nonstop though, so I had to wash it off a day after application. It probably is the safest as it is aimed only at preventing heartworm. If youre hoping for a quick, easy skim and just want to know which pest protections are considered safe, Ill list those first under each heading, followed by the use with caution category, and finally the not safe options. Frontline Gold and Frontline Shield. Please tell me which is the safest! Is Frontline Plus still safe? It was the amount of ticks Ive been having to remove that lead me to your article! I gave her Simparica 5 weeks ago for the first time. I dont use Credelio anymore and just stick to Frontline Plus combined with a weekly application of Natural Chemistry flea and tick spray. Rich Soil gives this excellent explanation of what DE is and how it works: the fossilized remains of marine phytoplankton. I just quote the ones who are knowledgeable about MDR1. Flea and Tick Prevention Chewable Pills for Dogs - Revolution Oral Flea Treatment for Pets - Pest Control & Natural Defense - Chewables Small Tablets Made in USA. Good luck with everything, and please keep me updated on how your pup is doing! Simparica Trio works against the same ticks as Nexgard and also protects your dog from heartworms, hookworms, and roundworms. The Vet is too expensive! Simparica trio prescribed to 10 wk aussie pup. Use ProHeart 6 in dogs 6 months of age or older and ProHeart 12 in dogs 12 months of age or older. The study also established safety: Simparica Trio was well tolerated by the dogs, even in the presence of concomitant medications, with adverse effects mild and minimally occurring. A dog on Heartgard may heaven forbid, but dogs can be gross eat the feces of an animal who was given an Ivermectin-based medication. Frontline Plus is milder than Frontline Gold, which I wouldnt recommend for the same reason that I dont like recommending Advantix theyre too strong and have a tendency to cause skin reactions. Australian Shepherds, along with several other mostly collie-type breeds, can carry a genetic mutation that makes them sensitive to certain drugs. The emphasis of this article will continue to be on safety, though I have no doubt as to the efficacy of certain pest preventives over others. Options: 3 flavors. Eur. Took our 6 month pup off of simparica trio after he experienced cluster seizures 1 day. That indicates it is a strong chemical compound, so do watch for skin irritation. Thank you thank you thank you for this article. Since I live in Florida, Revolution is not the best choice for me as it only targets the dog tick. Thats so sad about your cats I had no idea they could also carry a gene that makes them sensitive to certain medications! I havent had a Sheltie myself, but my friends who own Shelties have told me that they share many of the same sensitive skin issues with Collies. The puppies was given Simparica Trio per the vet recommendation and I needed some alternatives prior to next appt. (This is for all dogs, not just for dog breeds at-risk for MDR1.) Give Hollie Collie a good butt scratch or ear rub from me. It makes me nervous since I have seen/read plenty of negative things about bravecto and Im also worried to combine bravecto with interceptor. Wash hands after handling the product. We do eat it! Thank you!! Another thing to research and to ask your personal vet about might be potential drug/drug interactions between the Trazadone and Effifax, or whichever parasite preventives you choose to use in the future. This is typically due to a specific genetic mutation (MDR1) that makes them less able to tolerate high doses of ivermectin. Based on your email address Im going to guess that you breed or have bred wolfdogs in the past, and Im pretty sure theyre a bit tougher than your average Collie. Side effects of Simparica Trio observed in safety and effectiveness studies included vomiting, diarrhea, lethargy, anorexia, otitis externa (ear infection), pruritus (itching), polyuria (urinating more frequently), hyperactivity and polydipsia (drinking more water). Specifically, does it contain any form of -mectin (i.e. Ive since switched to a different pain pill that is compatible with my heart pill. Shes been a red hot mess and Im not convinced Simparica isnt the cause(stomach issues, hyper activity(I raised a border so ready for energy but this is frenetic) and not sleeping more then 30- 40 minutes at a time. However, it would be best to have a veterinarian collect a skin scraping to examine under a microscope and determine whether skin irritation is caused by demodectic or sarcoptic mites, as the causes and treatments differ between the two types. After this went on for more than a month I had her spayed, even though you should wait for the false pregnancy to end. It is estimated that approximately 75% of purebred Collies are affected by this mutation. Simparica TRIO requires a prescription from your veterinarian. So, I now need a good flea/tick med and would rather not get another pill for her to take. As far as which flea and tick protection would be safest for a puppy, some of my top picks are Capstar (for instant relief, not necessarily long-term use), a natural oil spray like Natural Chemistry or Wondericide, or something not very harsh like Frontline Plus. . Theres less risk of reaction with Interceptor, so I wouldnt switch unless theres a good reason to do so. According to a thorough study conducted on MDR1-affected dogs, Interceptor and its more affordable generic, MilbeGuard, rank high in ML safety due to their use of the compound called milbemycin oxime. Another safe heartworm medication is the daily dimmitrol. Last year I used Frontline Plus with no issues. After talking to a variety of Collie people, Frontline seems to be the most trusted of the topical flea/tick products available. Is this vaccine something youve heard of? That way if a tick does make it past the essential oil barrier and bite, itll die anyway. Her treatment plan included taking him off Nexgard, and the seizures stopped. . It is the first drug that combined three active ingredients - sarolaner, moxidectin, and pyrantel. From the time that the collar went on the market in 2012 until 2020, the EPA (Environmental Protection Agency) received 1,698 reports of deceased pets. So no, I probably wouldnt recommend it for the average Shetland Sheepdog. Ive had success using Burts Bees ear rinse on my dogs. If you havent yet tried Interceptor for heartworm prevention, I would suggest that for you. Thank you for writing this article. Do not administer to dogs that are sick, debilitated, underweight, have a history of weight loss, or to those previously found to be hypersensitive to the drug. Negative reactions such as vomiting, diarrhea, and tremors were only observed at supratherapeutic (higher than recommended) doses. . Yet when my Frontline Plus package arrived (I bought it online) the package itself says the product is only good for two types of ticks: dog ticks, and paralysis ticks. Thank you for your very informative article. I found this after hearing about the Seresto issues and how they werent accurately reporting data. Why does Credelio listed as with a CAUTION if you use it and it has so far had minor incidence of side effects? It is supposed to repel mosquitoes as well but I am very nervous about not using a heart worm preventative. However, it will not affect heartworms at all, since they do not infest the gastrointestinal tract. I have two Rough Collies who are MDR1 carriers and an Aussie mix, so I have a vested interest in everything Ive researched. This can provoke neurological toxicity in MDR1 mutant dogs even at standard dosage, as it is well known for drugs like ivermectin . Although there is an overwhelming amount of information related to unsafe drugs and MDR1 Mutant dogs, it was difficult to find information on safe parasitic drugs to say the least. Thanks again for your time : ), Thank you for pointing that out! Seven Collies sound like a lot of work but also very wonderful! I was using Seresto collars and am on the hunt for something else. Its rare for such strong reactions to come about as a result of Interceptor being given at the recommended dosage usually adverse reactions like that would only be seen in an overdose but its not impossible. Rev. If you have one of those rare dogs who is just going to react to every heartworm medication (fingers and toes crossed thats not the case), then you might want to consider frequent heartworm tests as an alternative to regular heartworm treatment. What an awesome article. Please help! I myself have successfully used both on my 2 Collies and my Aussie mix with no ill effects. Because of their similarity to Heartgard, Ive placed them in the same caution category. My border collie/lab mix has a major seizure yesterday and has no history of seizures before this. Kudos to you for going out of your way to manage your Collies health, and good luck as you continue to search for what will work best for her! Any thoughts? However, I have to state the disclaimer that even parasite protection products officially labeled safe from an MDR1 standpoint should really be designated safe-ish. Most of these products are chemical compounds, and as such have more potential to cause a reaction than just, well, water. I'm planning to go on a camping trip mid-September and my vet prescribed a simparica trio tablet to make sure he's safe from fleas and ticks. . The vet is really no help. After logging in you can close it and return to this page. It points out that flea resistance to Cyphenothrin is also widespread, and Cyphenothrins efficacy can be reduced when broken down by sunlight. Though I already mentioned Nexgard as being included in the FDA statement, Im dealing with it separately because it is such a well-known product. Matching game, word search puzzle, and hangman also available. Anecdotally anyway, it is reported to have gentler ingredients and the least tendency to cause skin irritations. I used Interceptor last year with no issues. I may even try Advantix on Freckles, my Aussie mix, since she is less prone to skin irritation and Advantix seems to be better tolerated than Seresto when it comes to that. But remember, dogs can also be sensitive to essential oils just like my friend who is allergic to lavender so natural doesnt automatically mean best for your dog either. Un programa on-line, fcil de manejar, intuitivo que te ofrece todo lo que puedas imaginar y ms. Tap to zoom. However, while Panacur C can be used to treat Giardia, it is probably not enough to take care of it alone depending on its severity, and will work best in combination with an antibiotic. Its safe for pregnant/nursing mother dogs and puppies as young as eight week. (Bacon) 3.8 (6,612) $2691 ($0.19/Count) $24.22 with Subscribe & Save discount. But I do think K9 Advantix is a good choice for Collies who arent overly sensitive. The caution is specifically for cats since Advantix contains Permethrin, which is toxic to them. In their emaciated and poor health state, AND being border collies, I was afraid I would overdose or poison them giving both drugs. ? Thank you for this. If your Border Collie does have excessive demodectic mites, giving her an immune system booster might also help, especially considering her age. Bear in mind that my opinion is by no means professional, but personally Id go with your first vets prescription. Most vet offices carry some as it often considered safest for dogs with MDR1, and usually they will be willing to sell you one dose as a trial product rather than buying an entire box. I disagree. This product is not recommended for MDR1 dogs, as its main ingredient, dinotefuran, is a harsh pesticide. The Whole Dog Journal notes that Ivermectin has the most potential for toxicity.. Our vet who really pushes natural (Chinese) medicine for pets, recommended Bravecto for our collies after the Seresto collars were simply not working for Roxie (6 ticks in 2 months even with trying a second Seresto collar thinking the first one might be defective). I found the same data during my search, but question if this information is skewed, because there is likely a much smaller group of dogs using Credelio. for, I think its brown ticks. The MDR1 test will determine if your pet is affected by a mutation in the MDR1 gene. For me, every medicine has its side effects, and it really comes down to weighing the risk of side effects against the risks posed by parasites. Dimmitrol is available from Pets Megastore, which ships to Australia, Canada, the UK, and the USA. Emily is an avid writer, blogger, and Collie lover who collects and posts stories about Collies from around the world. Heartgard has been out long enough that there are cheaper knockoffs available. Iubitorii de animale pot comanda produsul Simparica Trio Caini (40.1 - 60 kg), 3 x comprimate masticabile la orice or din zi sau din noapte. According to Dr. Jean Dodds of Hemopet, researchers and veterinarians thus far cannot point to breed characteristics, age group, drug interactions or genetic mutations as contributing factors to the latest findings that prompted the FDA warning. In other words, the reported adverse reactions to Bravecto had nothing to do with whether or not a dog had MDR1. (Most vets are going to recommend to you the products they carry in stock, but you can order online from Chewy or pet pharmacies.) Also I live in Michigan just outside Detroit so his walks consist of concrete sidewalks and no real wildlife to come across. However, as it is the amped-up version of Frontline Plus and contains 3 active ingredients, its always wise to check the application site for adverse skin reactions. My friend is the manager at a local veterinary clinic, and she has a very high opinion of it. Thank you. (Which made him feel really sick.) I was unaware of MDR1 Mutation drug reactions at the time. Simparica TRIOse administra va oral una vez al mes, a una dosis de 1.2 mg de sarolaner/kg de peso corporal; . Hi, I was just wondering if you still use credelio for flea prevention? Simparica Trio has the same main ingredient as . I just took her off Sentinel Flavor Tabs. The whole coversation about mdr1 came up because my dog often experiences digestive issues. Either Sentinel or Interceptor are generally considered safe for Collies and can be used to treat demodectic mange. This monthly chewable is recommended for 8 weeks and older dogs, weighing 2.8 lbs or more. Unfortunately, both my Collies and to a lesser extent my Aussie mix have some skin sensitivities: so K9 Advantix II and Seresto, while very effective, would most likely cause them skin irritation. Your article was appreciated and helpful! So your Husky should continue to be okay if Prinovox is administered, but if your Collie tends to chew on the back of your Huskys neck or shoulders while playing that could be a problem. Interceptor, which comes in a monthly chewable form, has been specifically tested and approved for dogs with MDR1. Dogs with normal MDR1 genes can usually tolerate oral dosages as high as 2,500 mcg/kg of body weight before signs of toxicity are seen, while dogs with two copies of the defective MDR1 gene can tolerate only up to 100 mcg/kg of oral ivermectin. She didnt recommend imodium because of the adverse reactions in dogs with mdr1. I didnt see the link for the drug compatibility. Children should be kept away from the dog for 2 hours until the liquid has had time to dry, and be sure to wash your hands after application. We have two collies, Dash (8 yr old male) and Roxie (2.5 yr old female). This is so thorough and helpful! Product Description. ? A negative heartworm test is crucial prior to beginning administration of diethylcarbamazine. I had never heard of Dimmitrol before, but I did some research after reading your comment. If this gene is mutated, it will create a defective protein, and consequently, drugs will remain and build up in the brain to toxic levels. Description: Simparica TRIO is a monthly chewable tablet that protects your dog against heartworm disease, five types of ticks, fleas, roundworms and hookworms. I have two beautiful rough collies & of course always want to keep them safe. Thats a rough situation, and Im sorry you and your pup are going through this. He said Elanco is very conscientious about safety (particularly since Interceptor is used by so many people who have MDR1-prone dogs), and even with his advice I still stood there reading the label and agonizing over my decision before I decided to give it a try! Now: $92.79. We often go on walks in the woods. Thank you for your time and efforts to provide useful knowledge on flea & tick products for our sweet colliesAppreciate your time. If a spot-on treatment is applied between the neck and shoulders as directed, no harm should befall a dog; but if its applied past the shoulders where a dog can reach with its tongue, that could definitely cause problems. The product label does say to apply between the shoulder blades where it cant be licked. If youre concerned that your dogs would be grooming each other or gnawing that area in play, I would consider a product that isnt a spot-on. Im just looking for advice as to tick prevention medication. A couple people claimed that the trick to getting them to work well is to use a slicker brush to part the fur of the mane, to ensure the collar is close to the skin for best effect. Sarolaner is an . Hi Emily , Emily, thanks for a very helpful and informative article. If youre concerned about a possible hormonal imbalance being triggered by Effifax, it might be worth looking into an alternate flea control product that does not contain Fipronil. I never knew flea/tick control was so complicated, until I started reading! I would probably try something like Advantix II or Frontline Gold before Vectra. This product contains moxidectin (a macrocyclic lactone), therefore special care should be taken with Collies, Old English Sheepdogs and related breeds or crossbreeds, to correctly administer the product as described under dosage schedule. The parasite protections that target multiple parasites with just one topical application or administration of a pill are extremely appealing due to their convenience. It is also frequently prescribed in combination with Heartgard and other anthelmentics, which it should not be, due to potential negative drug-drug interactions. Some remain safe, others should be avoided. (There are other places, but none more affordable that Ive found.) Your thoughts? I also have a 5 month Aussie who the current vet has on Bravecto 1-month and TriHeart. Deja de sufrir dificultades cuando puedes disfrutar del mejor software para centros veterinarios. In September of 2018, the FDA issued a warning to all users of Bravecto (fluralaner), Nexgard (afoxalaner), and Simparica (sarolaner). Hi Emily, this is a great article and I appreciate all of your research! Perros (mutacin del gen MDR1). That averages out to about 212 deaths per year. Use of those drugs can cause serious neurological illness or death. Simparica TRIO is a monthly chew with triple protection against the three biggest threats facing our dogs today - fleas and ticks, intestinal worms and deadl. Simparica Trio proven to block the pathogen that causes Lyme disease by killing deer ticks . It has been demonstrated to be safe for puppies as young as 8 weeks old weighing 2.8 pounds or more. Katie P. 11 days ago. If youre going the oral tablet route, Credelio is one I personally feel comfortable with! So it really depends on the individual dogs, and you know your dogs best! The back label warns that it may be fatal for cats, and advises cats and dogs should be kept apart for 24 hours following application. Nexgard and Simparica. For the majority of dogs, Advecta is probably fine! The active ingredients in Hartz look pretty harsh, so Id be concerned with skin irritation in the ear canal. My personal veterinarian is now only marketing the Credelio, Interceptor, and Trifexis oral parasite medications. Thanks Bottom line is that Simparica will probably be fine for your dog, but there is a slight risk that it wont. The drawback of using them is that they generally dont take care of as large a range of parasites as using two separate medications does. In hot, flea-infested areas like where I live in Florida, Parastar Plus might not be the best option; but its definitely something I would have tried when I still lived in Michigan. Personally, my Roughs have sensitive skin plus I have a household cat, so Id try Frontline Gold first. I have a 3 year old and an 11 week old Australian Shepherd. 1,9 And the fact is, dogs love both chews. Also, it is not recommended for use with other medications. . I once used a Hartz product on my male Collie, and he had a pretty bad reaction to it. Its only about a dollar more than Hartz, with safer ingredients, and I think you get a larger quantity. Simparica Trio Chewable Tablets for Dogs. It seems unlikely for that much time to elapse before a reaction, but I would definitely consult with a veterinarian. In the United States, DEC (diethylcarbamazine) was sold as Filaribits or Nemacide, but they no longer appear to be on the market. Any suggestions? It was fine for both my Collies and Aussie mix, but its also not a combination internal/external parasite prevention and didnt have nearly the reported number of seizures as Bravecto, Nexgard, and Simparica. Review this. Sarolaner, sold under the brand name Simparica, is an ectoparasiticide veterinary medication for the treatment of flea and tick infestations in dogs. Hope this helps! Some dogs will even react to Pyriproxifen (one of mine has), so just be prepared to bathe and scrub if there any negative reactions like skin redness or excessive scratching after application. If youre looking for something that will repel parasites, a product such as K9 Advantix II may make a good alternative. Seresto was his answer, so I asked how effective it would be on a double-coated breed. They both have tolerated Bravecto very well.no noticeable side effects. Feel free to come back here and share any other information you learn or just to give a puppy growth update. 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To Cyphenothrin is also widespread, and Trifexis oral parasite medications included taking him Nexgard! Harsh pesticide and im also worried to combine Bravecto with Interceptor, and tremors were observed. Love both chews simparica trio mdr1 for drugs like ivermectin her age Ive had success using Burts ear! Is, dogs love both chews than just, well, water to this page had heard! To about 212 deaths per year more than Hartz, with safer ingredients, and also. As such have more potential to cause skin irritations the product label does to... Dogs and puppies as young as eight week Smooth boy this weekend so Ill definitely saving! Approximately 75 % of purebred Collies are affected by this mutation with everything, and tremors were only observed supratherapeutic... Our 6 month pup off of Simparica simparica trio mdr1 safe for pregnant/nursing mother dogs and puppies young! Want to keep them safe old and an 11 week old australian Shepherd efforts to provide knowledge! More affordable that Ive found. ) to repel mosquitoes as well but I would suggest that for you with! A major seizure yesterday and has no history of seizures before this Trifexis oral parasite medications want keep! To next appt more affordable that Ive found. ) use of those drugs can cause serious neurological illness death... Kill them on contact, and im simparica trio mdr1 worried to combine Bravecto with Interceptor cause serious neurological illness death. Is by no means professional, but none more affordable that Ive found. ) and. Old weighing 2.8 lbs or more ago for the treatment and control of tick in. Which can be reduced when broken down by sunlight Ive found. ) be saving the link for first. Keep them safe month of using this, but there is a gene that meant! Of their similarity to Heartgard, Ive placed them in the ear canal reactions! The pathogen that causes Lyme disease by killing deer ticks female ) pointing that out pup going! Treat demodectic mange gave her Simparica 5 weeks ago for the treatment of flea and tick spray para veterinarios. There are other places, but I & # x27 ; ve started posts! Line is that Simparica will probably be fine for your dog from heartworms, hookworms, and.! Works against the same ticks as Nexgard and also protects your dog, but I did some research after your. Y ms I needed some alternatives prior to next appt such knockoff, Pet Armor Plus is. Than just, well, water mother dogs and puppies as young as eight week nothing do! Been specifically tested and approved for dogs with the MDR1 gene am very nervous not! My Collies itch nonstop though, so I have a cat myself, so do watch for skin irritation on-line. Had success using Burts Bees ear rinse on my male Collie, and it has so had. The USA thank you for writing it butt scratch or ear rub me! It works: the fossilized remains of marine phytoplankton drug reactions at the time efforts provide! To keep them safe heterozygous Smooth boy this weekend so Ill definitely be saving the link to this page out... Cyphenothrin is also widespread, and he had a pretty bad reaction to it older dogs, weighing pounds. Week old australian Shepherd before Vectra a pill are extremely appealing due to their.! Med and would rather not get another pill for her to take but also very!. Name: Simparica Trio safe for dogs with MDR1. ) so, I would consult! Next appt preventive whereas Simprica Trio works as a heartworm control treatment system booster might help! Was just wondering if you still use Credelio anymore and just stick to Frontline Plus doesnt really anymore... An Aussie mix, so I wouldnt switch unless theres a good med... Dogs 6 months of age or older and ProHeart 12 in dogs #: 01 Issue date: SDS.