Trends Microbiol 2009; 17: 406413. Although there have been several reports of pregnant people turning their toilet seats blue, there's no research connecting chromhidrosis and pregnancy. Fig. These infections usually go away on their own. Learn more here. Coughing up blood or mucus. The samples were cultivated aerobically, anaerobically, and for fungi. Mapara A TV, Khandelwal AK. Bacillus cereus, a volatile human pathogen. Generally speaking, the virus is most likely to spread from the time your symptoms . What is the latest research on the form of cancer Jimmy Carter has? Fluorescent material on dorsal aspects of the feet (especially interdigitally). Because it develops in the skin folds, inverse psoriasis can cause significant discomfort and distress. Chromhidrosis is a disorder of the sweat glandsthat manifests with colored sweat on the face, in the underarms, or on the areola of the breasts (the darker circle of skin around the nipples). (37). Infect Immun 2018; 86; e0008618. Review of reported cases of chromhidrosis. You may sweat so much that it soaks through your clothes or drips off your hands. He had no significant past medical history, underlying dermatoses, and did not use any medication. Chromhidrosis does not threaten your health. Arch Dermatol Res 2002; 294: 131134. Dermatol Online J 2012; 18: 13. Park JG, Prose NS, Garza R. Eccrine Chromhidrosis in an adolescent with sickle cell disease. You may sweat so much that it soaks through your clothes or drips off your hands. However, stress or embarrassment about the coloration can lead to depression and anxiety. In order to assess for a potential underlying cause of B. cereus growth, she was scheduled for a second appointment. Four bacteria are known to be involved in infectious pseudochromhidrosis: Bacillus spp. Barankin B, Alanen K, Ting PT, Sapijaszko MJ. Bilgin I, Kelekci KH, Catal S, Calli A. Late-onset apocrine chromhidrosis. Symptoms usually appear within one to two days of exposure. 4. Some people experience a warm or prickly feeling caused by stress or physical activity before colored sweat appears. Its wise to see a doctor about colored sweat. Chromhidrosis has several subtypes, which are described separately on DermNet. The infectiousness of this disorder has been exemplified in other studies (36, 44) as well as by the current case report. For evaluation of abnormal colored sweat or any other skin problem, contact our, Current and prospective patients can also. information submitted for this request. J Clin Diagn Res 2013; 7: 243246. Disclaimer. Dr. Hines has extensive experience in both common and rare conditions. Some people may benefit from therapy, counseling, medication for anxiety or depression, or a combination of these approaches. If you're dealing with discolored sweat, schedule a visit with a dermatologist to get answers, rule out more serious conditions, and learn about treatment options. Hyperhidrosis. Transient hypohidrosis induced by topiramate. AMA Arch Derm Syphilol 1954; 69: 449471. Rodriguez-Martin M, Rodriguez MS, Cabrera AN. Here's what experts have managed to suss out about this puzzling skin condition so far: Apocrine, eccrine and pseudochromhidrosis each show up a bit differently and have their own underlying causes, Daniel Friedmann, MD, board-certified dermatologist at Westlake Dermatology in Austin, Texas, tells LIVESTRONG.com. Debra Sullivan, Ph.D., MSN, R.N., CNE, COI, Butt sweat: Why it happens and how to get rid of it, a general feeling of hopelessness, worthlessness, helplessness, guilt or pessimism, a persistent anxious, sad, or empty mood, a decrease in energy or increase in fatigue, a lack of interest in once enjoyable activities, trouble concentrating, making decisions, or remembering, stimuli such as anxiety, sexual arousal, or pain, certain medications, such as bisacodyl, a laxative, when it is coated in tartrazine, a yellow dye, applying a capsaicin cream once or twice a day, though this can cause a burning sensation. These symptoms can include: There are a few possible causes of chromhidrosis, depending on the type. Electrophysiological study in 2 children with transient hypohidrosis induced by topiramate. Chromhidrosis is a rare condition characterized by the secretion of colored sweat. ALP had also been above upper reference limit prior to the presentation of blue discolouration (with no known or suspected cause). Case reports of infectious pseudochromhidrosis and causative microorganisms. Based on the literature review, there are only 4 bacteria that are confirmed to have resulted in cases of IPCH (Table I): Bacillus species blue IPCH (2, 37, 38): Bacillus is a genus of Gram-positive, sporulating rods that are aerobic or facultatively anaerobic and are widely distributed in the environment (soil, dust, water, food, and plants) (52, 53). Pink eye (conjunctivitis) generally remains contagious as long as your child has tearing and matted eyes. Drug Intell Clin Pharm 1978; 12: 674679. Eccrine chromhidrosis is generalized discolouration that occurs secondary to ingestion of water-soluble drugs (2, 27, 28), dyes (2931), or due to breakdown products from eccrine glands (2, 3235). Key words: chromhidrosis; pseudochromhidrosis; infectious pseudochromhidrosis; coloured sweat; pigment. 1). Clinical Neuropharmacol 2008; 31: 339346. About the International Hyperhidrosis Society. It may be associated with hyperhidrosis. Hines Dermatology Associates Inc., Attleboro, MA, Highly regarded dermatologist and dermatopathologist. Epilepsia 2003; 44: 974976. Chromhidrosis is a rare idiopathic disorder characterized by colored secretions most typically from the malar cheeks, axilla, or areolar regions. Williamson et al. nov.: proposed name for a black-pigmented Corynebacterium species recovered from the human female urogenital tract. National Library of Medicines list Chromhidrosis. [A woman with blue sweat]. Cox NH, Popple AW, Large DM. All rights reserved. is chromhidrosis contagious. Appl Environ Microbiol 2009; 75: 493503. "Your doctor can run the necessary tests to rule out more serious causes of colored sweat, such as infection, jaundice, hematidrosis (bloody sweat) and poisoning," Hadley King, MD, New York City-based board-certified dermatologist, tells LIVESTRONG.com. Uzoma M, Singh G, Kohen L. Green palmoplantar vesicular eruption in a patient with hyperbilirubinemia. The oxidation may be triggered by chronic exposure to copper (e.g. Apocrine chromhidrosis affects the areas of the body that contain apocrine sweat glands. It is well known that the bacteria can colonize moist skin surfaces and can cause a greenish discolouration of skin, nails, clothes, and surgical dressings (48, 62, 64, 65). Heider SA, Peters-Wendisch P, Wendisch VF. Only a few species, however, have been identified to produce carotenoid pigments (e.g. Infect Immun 2007; 75: 40624070. American Academy of Dermatology Association. And the sweating usually happens on both sides of the body. International Hyperhidrosis Societyhas received theGuideStar Exchange Seala leading symbol of transparency and accountability provided by GuideStar, the premier source of nonprofit information. Derivatives of the skin. Additional investigations were performed, including blood and urine analyses. that produced black pigment (with the proposed name C. nigricans) (97). J Bacteriol 2010; 192: 30683077. Role of melanin pigment in expression of Vibrio cholerae virulence factors. Corynebacterium nigricans sp. Those substances might include water-soluble dyes, heavy metals (like copper), excess food coloring or flavoring, as well as certain medications (rifampin, an antibiotic; quinines, an antimalarial; and levodopa, a dopamine precursor used to manage Parkinson's). While it isnt life-threatening, chromhidrosis often causes emotional distress. Labouche F. Pseudochromhidrose infectieuse: une tude de cas et une revue de la littrature. Erlangen: Caister Academic Press, 2008. Oliveira et al. Sometimes an underlying condition may be found and treated. All rights reserved. The isolates were initially identified by morphology, Gram stain, haemolysis on blood agar, penicillin susceptibility, and motility. There is a problem with Your body has two types of sweat glands, apocrine and eccrine. Others may have such mild sweat discoloration that they do not even notice it. Saff DM, Owens R, Kahn TA. Journal of the American Academy of Dermatology. Posted at 18:52h in houses for rent in sanger, ca century 21 by sabinas mountain boerne, tx. Australas J Dermatol. Chang T, Rosch JW, Gu Z, Hakim H, Hewitt C, Gaur A, et al. He or she will likely want to take the necessary steps to rule out potentially more serious medical conditions before making a diagnosis of chromhidrosis. Pediatr Dermatol 2017; 34: e273e274. Copper was normalized in this blood sample. If we combine this information with your protected This is a pigment that is produced as a byproduct of the oxidization of lipids (fats) in some types of cells. Front Microbiol 2017; 8: 1937. Other causes of bronchitis aren't contagious. Geelhoed-Duijvestijn PHLM. As you produce sweat, the body cools down. Mayo Clinic. All swabs and skin scrapings were negative for fungi. Kitamura S, Yanagi T, Imafuku K, Hata H, Shimizu H. Lipofuscin deposition causes the pigmentation of apocrine hidrocystoma. The blue colour was present continuously, but was more obvious after physical activity. The same authors also described resolution of both the blue skin discolouration and the Bacillus spp. Table II sums up potential triggers of IPCH based on the literature review. Hand-foot-and-mouth disease is a mild, contagious viral infection common in young children. From a medical perspective, the pathogenic species C. diphtheriae (diphtheria), C. ulcerans (diphtheria-like infections), C. tenuis (trichomycosis axillaris), C. minutissimum (erythrasma), and C. striatum (endocarditis) might be of greatest interest. People with chromhidrosis may have more lipofuscin, or lipofuscin that is more oxidized, than others. N Engl J Med 2004; 351: 1666. Lycopene, the bright red pigment found in tomatoes, is one of the carotenoids produced (95). The first and senior author of this study saw the family of 3 approximately one year after presentation. This site complies with the HONcode standard for trustworthy health information: verify here. Glaser DA, et al. Anyone who has chromhidrosis should speak with a healthcare provider if they start to experience symptoms of emotional distress, depression, or anxiety. Correlation between pigment production and amino acid requirements in Bacillus subtilis. Bacillus cereus, a serious cause of nosocomial infections: epidemiologic and genetic survey. Lipofuscin is common in human cells, but for some reason people with chromhidrosis have higher concentrations of lipofuscin or lipofuscin that is in a higher-than-normal state of oxidation. Hyperhidrosis (hi-pur-hi-DROE-sis) is excessive sweating that's not always related to heat or exercise. They're fatty deposits of cholesterol caused by very high levels of triglycerides, a type of fat in your blood. No skin biopsy was performed. J Biochem 1977; 81: 843850. Bromhidrosis is foul-smelling body odor related to your sweat. Pediatr Dermatol 2018; 35: 448452. Molecular evidence of person-to-person transmission of a pigmented strain of Corynebacterium striatum in intensive careunits. PloS One 2018; 13: e0194346. Highly regarded dermatologist and dermatopathologist Yvonne Hines, MD, and the team at Hines Dermatology Associates diagnose and treat a full range of conditions affecting the skin, including rare conditions such as chromhidrosis. Clinical photographs. Chlorxanthomycin, a fluorescent, chlorinated, pentacyclic pyrene from a Bacillus sp. Red sweat. Keeping the area clean and wearing different clothes can help resolve and. Cases of red, blue, green, yellow, pink, and black sweat have been reported. It's also important to talk to your doctor about any emotional distress you're experiencing in relation to your chromhidrosis, as feeling self-conscious about it is totally normal, Dr. King says: "Although it's a rare condition, you're not alone there are therapists and counseling available to help you out. Insight of genus corynebacterium: ascertaining the role of pathogenic and non-pathogenic species. Potential triggers of infectious pseudochromhidrosis (IPCH). AskMayoExpert. If medication is the cause of your colored sweat, it should return to normal after the medication is discontinued. Two glands produce sweat: eccrine and apocrine glands. Heavy sweating can disrupt your day and cause social anxiety and embarrassment. Table I. While it isn't life-threatening, chromhidrosis often causes emotional distress. Marks JG, Jr. Clin Exp Dermatol 2009; 34: e373374. Eccrine chromhidrosis resembling clinical features of pompholyx with bile-like greenish pigmentation on the right palm and soles. The potential triggers, causative microorganisms, diagnostic approaches, and suggested treatments for infectious pseudochromhidrosis are addressed. The condition can be treated by addressing potential triggers and/or prescribing antibiotic/antiseptic therapies. Bernard K. The genus corynebacterium and other medically relevant coryneform-like bacteria. J Am Acad Dermatol 1989; 21: 418420. Chromhidrosis is harmless, but it can cause embarrassment or distress that may lead to depression or anxiety. The authors have no conflicts of interest to declare. 2. Indian Dermatol Online J 2017; 8: 4244. The pigments causing the colour palette seen in this disorder appear to be of major importance for microorganisms. Autofluorescence of clothing as an adjunct in the diagnosis of apocrine chromhidrosis. The B. cereus strains are referred to as B. cereus in the following text. In pseudochromhidrosis, a far more common disorder, sweat becomes colored after secretion from the sweat gland. It can occur weeks or years after infection with the TB bacteria. Indian J Dermatol Venereol Leprol 2014; 80: 579. Sweating is the body's mechanism to cool itself. With this condition, your sweat is colorless, but when it interacts with something else on your skin bacteria, dye, chemicals from cleaning products, say a color change occurs. Eccrine glands are distributed with varying density over almost the entire integument and excrete large amounts of sweat, containing mostly water and electrolytes (1, 3). Leonard et al. Here, learn about home care techniques and medical treatments that can reduce or stop the, Sweating in the area around the vagina is normal, but it can sometimes cause discomfort and irritation. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Bronchitis itself isn't contagious, but some of its causes are. There is no medical cause for this type of hyperhidrosis. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. from an intrauterine device or drinking water) and ammonium (9). Some people theorize that hormonal changes or certain ingredients in prenatal vitamins are behind the phenomenon, but we just don't have a clear answer. Full texts and reference lists were reviewed. reported that the production of prodigiosin is highly dependent on temperature, pH, and other environmental factors (86). In: Triage Protocols for Aging Adults. If your bronchitis is caused by a virus, you can be contagious for a few days to a week. Chest pain, or pain with breathing or coughing. Facial and axillary apocrine chromhidrosis. J Am Acad Dermatol 1981; 4: 481482. Treatment of chromhidrosis may involve reducing sweat. If youre dealing with discolored sweat, schedule a visit with a dermatologist to get answers, rule out more serious conditions, and learn about treatment options. Accessed June 29, 2022. Pediatrics 2005; 115: e239241. Chromhidrosis is a rare condition with a characteristic presentation of the secretion of colored sweat and was first reported by Yonge in 1709. Epilepsia 2001; 42: 13631365. Hand-foot-and-mouth disease is most commonly caused by a coxsackievirus. Valeru SP, Rompikuntal PK, Ishikawa T, Vaitkevicius K, Sjling A, Dolganoy N, et al. If you experience sweating in an unusual hue, talk to your healthcare provider. (c) Diffuse blue discolouration on the neck. Carotenoid biosynthesis and overproduction in Corynebacterium glutamicum. See below for methods for culture and identification of bacteria, and results. Gaffney DC, Cooper HL. The latter approach can stop the sweat from happening for up to 3 days at a time. If your bronchitis is caused by bacteria, you usually stop being contagious 24 hours after starting antibiotics. Many of these pigments are extracellular, and thereby able to colour the skin surface and/or stain clothes (85). Upper respiratory infection symptoms include coughing, runny nose, sneezing and throat pain. Apocrine chromhidrosis results in only yellow, green, blue, black and brown sweat. McGraw Hill; 2019. https://accessmedicine.mhmedical.com. Chromhidrosis can subdivide into three categories: Apocrine chromhidrosis, eccrine chromhidrosis, and pseudochromhidrosis (pseudo-eccrine chromhidrosis). The patient performed 15 min of indoor cycling and 15 min of treadmill running. Castela et al. eat food or drink liquids that are contaminated with norovirus, touch surfaces or objects contaminated with norovirus and then put your fingers in your mouth, or. ", Always Sweating in Your Sleep? Red facial pseudochromhidrosis. Eccrine chromhidrosis is the production of coloured sweat from the eccrine sweat glands. They're fatty deposits of cholesterol caused. Infectious Pseudochromhidrosis: A Case Report and Literature Review, Copyright Acta Dermato-Venereologica. Odanaka K, Iwatsuki M, Satho T, Watanabe M. Identification and characterization of a brilliant yellow pigment produced by Bordetella pertussis. 4). If sweat changes color, contact a doctor, who may rule out other causes before diagnosing chromhidrosis. It is more common than chromhidrosis. All bacteriological swabs of female patient (neck, upper arm, axilla, hand, and foot) had heavy growth of 2 strains of Bacillus cereus. Here's What Your Body's Trying to Tell You. Certain situations stimulate the apocrine glands and make this discoloration more likely to occur: In people with eccrine chromhidrosis, the discoloration usually happens because the person has ingested: Pseudochromhidrosis is more common, and it occurs when the skin comes into contact with: The IHS also point to other health issues that can cause sweat to change color: It is a good idea to see a doctor about colored sweat. We avoid using tertiary references. Lipofuscin is an intra-lysosomal polymeric material that gains colour as it oxidizes, with higher oxidation states resulting in a darker colour (1, 68). Symptoms include sores in the mouth and a rash on the hands and feet. J Bacteriol 1953; 65: 509510. Nair PA, Kota RK, Surti NK, Diwan NG, Gandhi SS. The pH of the skin surface and its impact on the barrier function. Ensminger PW. As neither MaldiTOF nor 16S rRNA can distinguish properly between the B. cereus, B. anthracis and B. thuringiensis, it was concluded that the isolates belong to the B. cereus group and are non-anthracis. International Hyperhidrosis Societyhas been awarded as a Top-Rated Nonprofit since 2012! Clin Auton Res 2015; 25: 153159. In other circumstances, health issues such as infection and liver problems may cause sweat to change color. SPORTS + SWEATING PLAYBOOK VOLUME 2: RUNNING COLD. Infections in those with higher risk may last longer. Shelley WB, Hurley HJ, Jr. Liu GY, Nizet V. Color me bad: microbial pigments as virulence factors. Heart failure: Could a low sodium diet sometimes do more harm than good? Current and prospective patients can also send a message to Dr. Hines and the team here on our website. Semkova K, Gergovska M, Kazandjieva J, Tsankov N. Hyperhidrosis, bromhidrosis, and chromhidrosis: Fold (intertriginous) dermatoses. JAMA 1977; 238: 1628. Banerjee D, Chatterjee S, Banerjee UC, Guha AK, Ray L. Green pigment from Bacillus cereus M(1)(16) (MTCC 5521): production parameters and antibacterial activity. One area of the body that commonly becomes sweaty is the feet. This tentative diagnosis has been strengthened by complete remission after antibacterial treatment, combining systemic and topical erythromycin in all cases. Sports + Sweating Playbook V2: Running Cold Winter Workout Tips to Avoid Frostbite & Hypothermia SPORTS + SWEATING PLAYBOOK VOLUME 1: GEAR. Review/update the Sweating a different color -- like yellow, blue, green, or black -- is a different condition called chromhidrosis. Symptoms are usually worse during the first 2 to 3 days, and this is when you're most likely to spread the virus. Apart from B. cereus, previous studies have also described pigment production in many other Bacillus spp. Eccrine glands secrete a clear, odorless fluid that. The end result is usually nothing more than sticky skin and the occasional pit-stained tee but for a small percentage of people, sweating can also leave behind a blue toilet seat. Articles in English, German, French, Dutch, and Danish were included. In a person with apocrine chromhidrosis, lipofuscin causes discoloration as part of the natural process of creating sweat. As such, some microorganisms invest heavily in pigment production, producing up to 30% of their dry weight as pigments (84). Galadari H, et al. An ashen hue was observed primarily on hands, feet, and neck (female patient), and right pectoral region (male patient). Sweat may be yellow, green, blue, brown, or black. In terms of pathogenic Bacillus spp., B. anthracis is the only obligate pathogen (where cutaneous anthrax represents 95% of cases worldwide) (53). 1Department of Plastic and Reconstructive Surgery, Rikshospitalet, Oslo University Hospital, 2Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, 3Department of Microbiology and Infection Control, Akershus University Hospital, 4Multidisciplinary Laboratory Medicine and Medical Biochemistry, Akershus University Hospital, and 5Akershus Dermatology Center, Lrenskog, Norway? Anyone can get an upper respiratory infection, though they happen more frequently among children. Balasubramanian S, Amperayani S, Dhanalakshmi K, Kumar R. Chromhidrosis colored sweat in a toddler. Acta Derm Venereol 2009; 89: 538539. Fig. Prodigiosin pigment of Serratia marcescens is associated with increased biomass production. Curr Genet 2015; 61: 309324. For evaluation of abnormal colored sweat or any other skin problem, contact our Attleboro, Massachusetts, office at 508-222-1976 or book online to schedule an appointment. J Clin Microbiol 2003; 41: 43534358. Red and black pseudochromhidrosis. To provide you with the most relevant and helpful information, and understand which Yellow pseudochromhidrosis in a young female. Shulka et al. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, International Hyperhidrosis Society (IHS), https://www.sweathelp.org/where-do-you-sweat/other-sweating/chromhidrosis.html, https://cdn.ymaws.com/www.aocd.org/resource/resmgr/jaocd/contents/volume30/30-05.pdf, https://adaa.org/understanding-anxiety/depression/symptoms, https://www.ncbi.nlm.nih.gov/books/NBK554395/. People sweat due to heat, stress, and a range of other causes. Accessed June 16, 2022. At the time of presentation, the patient was approximately 7 months pregnant with her first child. It often begins with antiperspirants. These glands are in the underarm and genital regions, as well as the scalp, torso, eyelid, outer ear canal and nipple areas. Treatment of apocrine chromhidrosis with topical capsaicin. The patient also reported staining of her clothes, towels, furniture, and shower. Pseudochromhidrosis can also happen at any age and stem from a variety of causes all of which are external in nature. Depending on the cause of your child's pink eye, signs and symptoms usually improve within a few days to two weeks. Australas J Dermatol 2016; 57: e2325. We report here a case of blue infectious pseudochromhidrosis caused by pigment-producing Bacillus cereus and the results of a literature review. Tempark T, Wittayakornrerk S, Jirasukprasert L, Chatproedprai S, Wananukul S. Pseudochromhidrosis: report and review of literature. IPCH following administration of an antihistamine. Infant with chromhidrosis. Avalos J, Carmen Limon M. Biological roles of fungal carotenoids. https://www.aad.org/public/diseases/a-z/hyperhidrosis-overview. (n.d.). Skin scrapings for dermatophyte PCR identification were taken from the female and male patient. Infectious pseudochromhidrosis is a rare dermatological disorder, characterized by a change in colour of the sweat from normal skin, caused by pigments from microorganisms. In other words, it's not your sweat that's colored the color comes from the way your sweat interacts with other things outside your body. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. You can take steps to avoid contagious or infectious skin diseases. Table II. Heavy sweating can disrupt your day and cause social anxiety and embarrassment. Dermatol Monatschr 1972; 158: 18. Wolters Kluwer; 2019. Yamada-Ankei T, Iwasaki H, Mori T. Production of copper coproporphyrin III by Bacillus cereus. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Book: Mayo Clinic Family Health Book, 5th Edition, Health Products for Men and Women from Mayo Clinic Store, Newsletter: Mayo Clinic Health Letter Digital Edition. Canale-Parola E. A Red pigment produced by aerobic sporeforming bacteria. Treatments may involve: However, authors of a review point out that current treatment options are limited and may not be very effective They emphasize the need for more research. Alongside Hills et al., the current case report presents a patient who might be affected by blue Bacillus spp. Regular sweat is clear or slightly cloudy in color. J Am Acad Dermatol 2012; 67: e7475. Singal A, Thami GP. Some people may experience a warm, tingly sensation before the appearance of colored sweat. There are documented differences in the pH and hydration between paediatric and adult stratum corneum (102). Kang S, et al., eds. Banerjee D, Mondal A, Gupta M, Guha AK, Ray L. Optimization of fermentation conditions for green pigment production from Bacillus cereus M116 (MTCC 5521) and its pharmacological application. J Clin Microbiol 1978; 8: 105107. Effect of prothazin (promethazine hydrochloride) on sweat gland activity. B. cereus is an occasional pathogen that can cause various infections mostly associated with its secreted toxins (5255). Taylor MJ, Lawton WD, Goldberg ID. It could be removed with soap and water; however, it was more easily removed with alcohol wipes (Fig. Williamson NR, Simonsen HT, Ahmed RA, Goldet G, Slater H, Woodley L, et al. On the contrary, the patient reported daily attacks of cholinergic and dermographic urticaria, and hypohidrosis even after strenuous exercise and emotional stimuli. Bottone EJ. Usually, chromhidrosis affects the apocrine glands, mainly on the face and underarms. There are three types of chromhidrosis: apocrine, eccrine, and pseudochromhidrosis. of signs you need emergency medical attention or call 911. Eccrine chromhidrosis can affect the skin over any body area but is often worst on the palms and soles where eccrine sweat glands are most concentrated. Combined use of ranitidine (H2-recepter antagonist) and lansoprazole (proton pump inhibitor) may trigger Bacillus colonization, as reported by Hill et al. information highlighted below and resubmit the form. 4). Matarasso SL. Microorganisms may produce pigments to increase the likelihood of survival. Int J Dermatol 2017; 56: 496502. Alcohol wipes from (a) hands and (b) neck easily removed the discolouration and revealed its blue colour. and Corynebacterium spp. Yamada-Ankei T, Iwasaki H, Mori T. Production of copper coproporphyrin III by Bacillus cereus. Pigments of Staphylococcus aureus, a series of triterpenoid carotenoids. These colors are due to a pigment produced in the sweat glands called lipofuscin.